Talking About Endocrinology…
R&D systems offers many tools for endocrine research including assay kits, antibodies, and proteins to study peptide hormones, steroid hormones, their receptors, as well as reagents to study eicosanoids.
The endocrine system is made up of glands or cell types that secrete regulatory hormones into the bloodstream. Primary endocrine glands include the pituitary, hypothalamus, thyroid, parathyroid, pancreas, testes, ovaries, and adrenal glands. The hormones they release modulate an array of physiological functions including metabolism, blood pressure, appetite, development, and reproduction. Hormones can be roughly divided into two classes, peptide/amino acid-derived hormones, and the steroid hormones, most of which are derived from cholesterol. The peptide hormones generally bind cell surface receptors and initiate signal transduction cascades, while steroid hormones are membrane permeant and bind intracellular receptors that modulate transcription. Serious medical conditions arise from endocrine gland dysfunction including diabetes (pancreas), Grave‚Äôs disease (thyroid), Hashimoto‚Äôs thyroiditis (thyroid), and Addison‚Äôs disease (adrenal gland). Please click the links below to find products associated with your area of interest.
Endocrinology is the study of hormones, their signaling pathways, and the diseases associated with them. The endocrine system is one of two mechanisms in the human body that is responsible for regulating and integrating the function of cells, the other being the nervous system.
Endocrine Disease Product Areas
Endocrinology Research Product Areas
Hormones are classified into three types, according to their chemical composition:
Peptide hormones produced by secretory nervous tissue are known as neuropeptides.
A disease due to a disorder of the endocrine system is often called a “hormone imbalance” and is usually caused by hypo- or hyperfunction of an endocrine gland. Better known examples include Acromegaly, Cushing Syndrome, Diabetes, Dwarfism, Graves Disease, Hermaphroditism, Delayed and Precocious Puberty, and Thyroid Diseases.