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Endocrinology

Talking About Endocrinology…

R&D Systems:

R&D systems offers many tools for endocrine research including assay kits, antibodies, and proteins to study peptide hormones, steroid hormones, their receptors, as well as reagents to study eicosanoids.

The endocrine system is made up of glands or cell types that secrete regulatory hormones into the bloodstream. Primary endocrine glands include the pituitary, hypothalamus, thyroid, parathyroid, pancreas, testes, ovaries, and adrenal glands. The hormones they release modulate an array of physiological functions including metabolism, blood pressure, appetite, development, and reproduction. Hormones can be roughly divided into two classes, peptide/amino acid-derived hormones, and the steroid hormones, most of which are derived from cholesterol. The peptide hormones generally bind cell surface receptors and initiate signal transduction cascades, while steroid hormones are membrane permeant and bind intracellular receptors that modulate transcription. Serious medical conditions arise from endocrine gland dysfunction including diabetes (pancreas), Grave’s disease (thyroid), Hashimoto’s thyroiditis (thyroid), and Addison’s disease (adrenal gland). Please click the links below to find products associated with your area of interest.
Bone Growth & Remodeling
Cellular Senescence & Pathways in Aging
Hormones & Receptors
Metabolism
Proteases
Reproduction
Signal Transduction

Tocris Bioscience:

Endocrinology is the study of hormones, their signaling pathways, and the diseases associated with them. The endocrine system is one of two mechanisms in the human body that is responsible for regulating and integrating the function of cells, the other being the nervous system.

Endocrine Disease Product Areas

Endocrinology Research Product Areas

Hormone Classification

Hormones are classified into three types, according to their chemical composition:

  • Amines (such as dopamine, adrenalin and noradrenalin)
  • Steroids (such as estrogen, testosterone and glucocorticoids)
  • Peptides (such as the peptide hormones insulin, ghrelin and vasopressin).

Peptide hormones produced by secretory nervous tissue are known as neuropeptides.

Endocrinological Dysregulation

A disease due to a disorder of the endocrine system is often called a “hormone imbalance” and is usually caused by hypo- or hyperfunction of an endocrine gland. Better known examples include Acromegaly, Cushing Syndrome, Diabetes, Dwarfism, Graves Disease, Hermaphroditism, Delayed and Precocious Puberty, and Thyroid Diseases.

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